General Western Blot Reagents
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Filtered Search Results
Abcam Fi x able Viability Dye (787/808), 50 TestsS
Labeling in < 4 hrs with 30 secs hands-on time using Fixable Viability Dye (787/808) ab314683. 100% antibody recovery.
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Abcam 3-Cyano-7-etho x ycoumarin, Fluorogenic cytochrome P450 monoo x ygenase substrate, 20MG
MW 215.2 g/mol, Purity >99%. Fluoreogenic cytochrome P450 mixed-function monooxygenase substrate. Metabolized to the fluorescent compound 3-cyano-7-hydroxycoumarin. About 50-100 times more sensitive than conventional substrate ethoxy-resorufin due to higher turn over rate.
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Abcam N-Palmitoyl phosphatidylethanolamine, Endogenous lipid anorectic hormone, 5MG
MW 930.4 g/mol, Purity >98%. Endogenous lipid which significantly reduced food intake in a dose-dependent fashion when administered to rats and mice without causing taste aversion. Found to enter the brain (concentrating in the hypothalamus) when administered systemically and also reduced food intake when infused intracerebroventricularly (nanomolar concentrations), suggesting that mediation of effects is via the CNS. Chronic infusion resulted in a reduction of both food intake and body weight, suggesting that NAPE and long-acting NAPE analogs may be novel therapeutic targets for the treatment of obesity.
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Abcam Agomelatine, MT1/MT2 agonist and 5-HT2C antagonist, 500MG
MW 243.3 Da, Purity >99%. Potent MT1/MT2 agonist (Ki values are 0.1 and 0.12 nM, respectively). 5-HT2C antagonist (IC50 = 270 nM). Shows antidepressant effects *in vivo*. Orally active.
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Abcam 4-O x o-2-nonenal (4-ONE), TRPA1 activator, 1MG
MW 154.21 g/mol, Purity >98%. Lipid peroxidation product, actively modifies histidine and lysine residues on proteins and causes protein cross-linking. Shows a variety of biological activities and is a TRPA1 activator (EC₅₀ = 1.9 μM). Active in vivo.
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Abcam (R)-Butaprost, EP2 agonist, 5MG
MW 408.6 Da, Purity >98%. Selective EP2 agonist. PGE2 structural analog. Inhibits chemotaxis (EC50 = 106 nM, maximal effect of PGE2). Increases neutrophil cyclic AMP levels.
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Abcam 7-Diethylamino-3-[N-(4-maleimidoethyl)carbamoyl]coumarin, Thiol-reactive fluorescent probe, 20MG
MW 383.4 g/mol, Purity >97%. Thiol-reactive fluorescent probe for protein labeling. Achieve your results faster with highly validated, pure and trusted compounds.
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Abcam CAY10498, A3 adenosine receptor antagonist, 5MG
MW 320.4 Da, Purity >98%. Potent, selective A3 adenosine receptor antagonist (Ki = 37 nM). Reversine (ab120921) analog.
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Abcam Human PTHLH peptide, 100UG
Human PTHLH peptide is a Synthetic blocking peptide. >95% purity and suitable for BL.
Protein/ Peptide/ Enzyme Synonyms: PTHRP, PTHLH, Parathyroid hormone-related protein, PTH-rP, PTHrP, Parathyroid hormone-like protein, PLP
Conjugation: Unconjugated
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Abcam AGK7, structural isomer of AGK2, 5MG
MW 434.3 Da, Purity >99%. Inactive control; structural isomer of AGK2 (ab142073) (SIRT2 inhibitor). Cell-permeable.
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Abcam PRIMA-1MET, p53 activity, 10MG
MW 199.25 Da, Purity >98%. Methylated derivative of PRIMA-1 (ab141641). Restores wild-type conformation and function to mutant p53, and triggers apoptosis in tumor cells. Acts synergistically with chemotherapeutic agents to inhibit tumor cell proliferation. Inhibits thioredoxin reductase 1 (TrxR1), a key regulator of cellular redox balance.
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Abcam NPS 2143 hydrochloride, Ca2+-sensing receptor antagonist, 10MG
MW 445.4 Da, Purity >99%. Potent, selective Ca2+-sensing receptor antagonist (IC50 = 43 nM). Stimulates parathyroid hormone secretion (EC50 = 41 nM). Shows antihypertensive effects *in vivo.* Orally active.
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Abcam Cysteamine hydrochloride, Degradation product of cystine, 100G
MW 113.61 Da, Purity >98%. Degradation product of cystine. Various pharmacological activities. Effective against cystinosis. Antitumor agent. Active in vivo.
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Abcam VAS 2870, NADPH o x idase inhibitor, 50MG
MW 360.4 g/mol, Purity >98%. NADPH oxidase inhibitor. Blocks PDGF-mediated NADPH activation and ROS production. Inhibits PMS-induced oxidative burst (IC₅₀ = 2 μM, HeLa cells). Shows anti-ischemic effects ex vivo. .
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Abcam Sodium o x amate, Weak lactate dehydrogenase inhibitor, 5G
MW 111.03 Da, Purity >99%. Weak lactate dehydrogenase inhibitor (IC₅₀ values are 600 and 4400 μM in H460 and A549 cells respectively). Inhibits glycolysis and gluconeogenesis. Pyruvate (ab145036) analog. Decreases extracellular acidification rate.
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